Asst. Prof. Şükrü Anıl Doğan, PhD, is a mitochondrial biologist whose research explores how dysfunction in cellular energy systems drives human disease and aging. His work bridges fundamental biochemistry with translational medicine, focusing on redox signalling, mitochondrial quality control, and tissue‑specific stress responses. By combining genetic mouse models, high‑resolution mitochondrial assays, and advanced transcriptomic tools, his lab uncovers the molecular mechanisms that underlie muscle wasting, inherited myopathies, and neurodegeneration.
Dr. Doğan's research has provided key insights into the dual role of reactive oxygen species in both pathology and adaptive signalling, the therapeutic potential of interventions such as rapamycin in mitochondrial disease, and the systemic metabolic changes that accompany cancer cachexia. Through collaborative and multidisciplinary approaches, his group advances mechanistic discoveries into therapeutic strategies, with the broader aim of developing biomarkers and treatments that can mitigate the impact of mitochondrial dysfunction in human health.
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